High Maternal Serum Estradiol Levels Induce Dyslipidemia in Human Newborns via a Hepatic HMGCR Estrogen Response Element

While the intrauterine environment is essential for the health of offspring, the impact of high maternal serum estradiol (E(2)) on lipid metabolism in offspring and the mechanisms are unknown. We found that ovarian stimulation (OS) could result in high E(2) levels in women throughout pregnancy. Stri...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Meng, Ye, Lv, Ping-Ping, Ding, Guo-Lian, Yu, Tian-Tian, Liu, Ye, Shen, Yan, Hu, Xiao-Ling, Lin, Xian-Hua, Tian, Shen, Lv, Min, Song, Yang, Guo, Meng-Xi, Ke, Zhang-Hong, Xu, Hong, Sheng, Jian-Zhong, Shi, Feng-Tao, Huang, He-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426719/
https://ncbi.nlm.nih.gov/pubmed/25961186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10086
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