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Trypanosoma cruzi Calreticulin Topographical Variations in Parasites Infecting Murine Macrophages

Trypanosoma cruzi calreticulin (TcCRT), a 47-kDa chaperone, translocates from the endoplasmic reticulum to the area of flagellum emergence. There, it binds to complement components C1 and mannan-binding lectin (MBL), thus acting as a main virulence factor, and inhibits the classical and lectin pathw...

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Foilsithe in:Am J Trop Med Hyg
Main Authors: González, Andrea, Valck, Carolina, Sánchez, Gittith, Härtel, Steffen, Mansilla, Jorge, Ramírez, Galia, Fernández, María Soledad, Arias, José Luis, Galanti, Norbel, Ferreira, Arturo
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society of Tropical Medicine and Hygiene 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426574/
https://ncbi.nlm.nih.gov/pubmed/25758653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.14-0497
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