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FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord

The remodeling of axonal circuits after injury requires the formation of new synaptic contacts to enable functional recovery. Which molecular signals initiate such axonal and synaptic reorganisation in the adult central nervous system is currently unknown. Here, we identify FGF22 as a key regulator...

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Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Jacobi, Anne, Loy, Kristina, Schmalz, Anja M, Hellsten, Mikael, Umemori, Hisashi, Kerschensteiner, Martin, Bareyre, Florence M
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426482/
https://ncbi.nlm.nih.gov/pubmed/25766255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490578
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