Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis

We have shown that cellular inhibitor of apoptosis proteins (cIAPs) impair clearance of hepatitis B virus (HBV) infection by preventing TNF-mediated killing/death of infected cells. A key question, with profound therapeutic implications, is whether this finding can be translated to the development o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ebert, Gregor, Allison, Cody, Preston, Simon, Cooney, James, Toe, Jesse G., Stutz, Michael D., Ojaimi, Samar, Baschuk, Nikola, Nachbur, Ueli, Torresi, Joseph, Silke, John, Begley, C. Glenn, Pellegrini, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426438/
https://ncbi.nlm.nih.gov/pubmed/25902530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502400112
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