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Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface

Surface-presented glycans (complex carbohydrates) are docking sites for adhesion/growth-regulatory galectins within cell–cell/matrix interactions. Alteration of the linker length in human galectin-8 and single-site mutation (F19Y) are used herein to illustrate the potential of glycodendrimersomes wi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhang, Shaodong, Moussodia, Ralph-Olivier, Vértesy, Sabine, André, Sabine, Klein, Michael L., Gabius, Hans-Joachim, Percec, Virgil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426414/
https://ncbi.nlm.nih.gov/pubmed/25902539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506220112
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