Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

A first-in-human clinical trial of ultrasmall inorganic hybrid nanoparticles, “C dots” (Cornell dots), in patients with metastatic melanoma is described for the imaging of cancer. These renally excreted silica particles were labeled with (124)I for positron emission tomography (PET) imaging and modi...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Phillips, Evan, Penate-Medina, Oula, Zanzonico, Pat B., Carvajal, Richard D., Mohan, Pauliah, Ye, Yunpeng, Humm, John, Gönen, Mithat, Kalaigian, Hovanes, Schöder, Heiko, Strauss, H. William, Larson, Steven M., Wiesner, Ulrich, Bradbury, Michelle S.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426391/
https://ncbi.nlm.nih.gov/pubmed/25355699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009524
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