A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains

The genetic variants underlying complex traits are often elusive even in powerful model organisms such as Caenorhabditis elegans with controlled genetic backgrounds and environmental conditions. Two major contributing factors are: (1) the lack of statistical power from measuring the phenotypes of sm...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Andersen, Erik C., Shimko, Tyler C., Crissman, Jonathan R., Ghosh, Rajarshi, Bloom, Joshua S., Seidel, Hannah S., Gerke, Justin P., Kruglyak, Leonid
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2015
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426375/
https://ncbi.nlm.nih.gov/pubmed/25770127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.017178
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