Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice

The non-obese diabetic (NOD) mouse is a polygenic model for type 1 diabetes that is characterized by insulitis, a leukocytic infiltration of the pancreatic islets. During ~35 years since the original inbred strain was developed in Japan, NOD substrains have been established at different laboratories...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:G3 (Bethesda)
Prif Awduron: Simecek, Petr, Churchill, Gary A., Yang, Hyuna, Rowe, Lucy B., Herberg, Lieselotte, Serreze, David V., Leiter, Edward H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2015
Pynciau:
Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426365/
https://ncbi.nlm.nih.gov/pubmed/25740934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.017046
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