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Disease course in mdx:utrophin(+/−) mice: comparison of three mouse models of Duchenne muscular dystrophy

The mdx mouse model of Duchenne muscular dystrophy (DMD) is used to study disease mechanisms and potential treatments, but its pathology is less severe than DMD patients. Other mouse models were developed to more closely mimic the human disease based on knowledge that upregulation of utrophin has a...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: McDonald, Abby A, Hebert, Sadie L, Kunz, Matthew D, Ralles, Steven J, McLoon, Linda K
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425985/
https://ncbi.nlm.nih.gov/pubmed/25921779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12391
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