INCREASED CLEARANCE OF CORTISOL BY 5β-REDUCTASE IN A SUBGROUP OF WOMEN WITH ADRENAL HYPERANDROGENISM IN POLYCYSTIC OVARY SYNDROME

OBJECTIVE: Increased peripheral metabolism of cortisol may explain compensatory ACTH-dependent adrenal steroidogenesis and hence hyperandrogenism in polycystic ovary syndrome (PCOS). Previous studies have described an increased 5α-reduction of cortisol or impaired regeneration of cortisol by 11β-HSD...

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Bibliografske podrobnosti
izdano v:J Endocrinol Invest
Main Authors: Gambineri, Alessandra, Forlani, Giulia, Munarini, Alessandra, Tomassoni, Federica, Cognigni, Graciela E., Ciampaglia, Walter, Pagotto, Uberto, Walker, Brian R, Pasquali, Renato
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425940/
https://ncbi.nlm.nih.gov/pubmed/19542736
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