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Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.

Regulation of tumor necrosis factor (TNF) gene expression was investigated in resting human monocytes and in 12-O-tetradecanoylphorbol-13-acetate (TPA) activated monocytes. TNF transcripts were undetectable in resting monocytes. However, in TPA-activated monocytes, TNF mRNA was first detectable by 3...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Sariban, E, Imamura, K, Luebbers, R, Kufe, D
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3366904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113482
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