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Use of laminar flow and unstirred layer models to predict intestinal absorption in the rat.

Carbon monoxide (CO) and [14C]warfarin were used to measure the preepithelial diffusion resistance resulting from poor luminal stirring (RL) in the constantly perfused rat jejunum at varying degrees of distension (0.05, 0.1, and 0.2 ml/cm). RL was much greater than epithelial cell resistance, indica...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Levitt, M D, Kneip, J M, Levitt, D G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3366899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113464
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