Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE(2) Mediated JAK2/STAT3 Signaling Pathway

Berberin, extracted from Chinese herbal medicine Coptis chinensis, has been found to have anti-tumor activities. However, the underlying mechanisms have not been fully elucidated. Our current study demonstrated that berberin inhibited the in vitro and in vivo growth, migration/invasion of CRC cells,...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Xuan, Ji, Qing, Ye, Naijing, Sui, Hua, Zhou, Lihong, Zhu, Huirong, Fan, Zhongze, Cai, Jianfeng, Li, Qi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425560/
https://ncbi.nlm.nih.gov/pubmed/25954974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123478
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