Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

OBJECTIVES: This purpose of this study was to examine clinical-pathologic factors – particularly smoking and brain metastases – in EGFR mutation positive (M+) lung adenocarcinoma (ADC) to determine their impact on survival in patients treated with first line EGFR TKI. METHODS: A retrospective review...

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Foilsithe in:PLoS One
Main Authors: Jain, Amit, Lim, Cindy, Gan, Eugene MingJin, Ng, David Zhihao, Ng, Quan Sing, Ang, Mei Kim, Takano, Angela, Chan, Kian Sing, Tan, Wu Meng, Kanesvaran, Ravindran, Toh, Chee Keong, Loo, Chian Min, Hsu, Anne Ann Ling, Devanand, Anantham, Lim, Chong Hee, Koong, Heng Nung, Koh, Tina, Fong, Kam Weng, Yap, Swee Peng, Kim, Su Woon, Chowbay, Balram, Oon, Lynette, Lim, Kiat Hon, Lim, Wan Teck, Tan, Eng Huat, Tan, Daniel Shao Weng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425557/
https://ncbi.nlm.nih.gov/pubmed/25955322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123587
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