Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

OBJECTIVES: This purpose of this study was to examine clinical-pathologic factors – particularly smoking and brain metastases – in EGFR mutation positive (M+) lung adenocarcinoma (ADC) to determine their impact on survival in patients treated with first line EGFR TKI. METHODS: A retrospective review...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jain, Amit, Lim, Cindy, Gan, Eugene MingJin, Ng, David Zhihao, Ng, Quan Sing, Ang, Mei Kim, Takano, Angela, Chan, Kian Sing, Tan, Wu Meng, Kanesvaran, Ravindran, Toh, Chee Keong, Loo, Chian Min, Hsu, Anne Ann Ling, Devanand, Anantham, Lim, Chong Hee, Koong, Heng Nung, Koh, Tina, Fong, Kam Weng, Yap, Swee Peng, Kim, Su Woon, Chowbay, Balram, Oon, Lynette, Lim, Kiat Hon, Lim, Wan Teck, Tan, Eng Huat, Tan, Daniel Shao Weng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425557/
https://ncbi.nlm.nih.gov/pubmed/25955322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123587
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