Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

OBJECTIVES: This purpose of this study was to examine clinical-pathologic factors – particularly smoking and brain metastases – in EGFR mutation positive (M+) lung adenocarcinoma (ADC) to determine their impact on survival in patients treated with first line EGFR TKI. METHODS: A retrospective review...

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Udgivet i:PLoS One
Main Authors: Jain, Amit, Lim, Cindy, Gan, Eugene MingJin, Ng, David Zhihao, Ng, Quan Sing, Ang, Mei Kim, Takano, Angela, Chan, Kian Sing, Tan, Wu Meng, Kanesvaran, Ravindran, Toh, Chee Keong, Loo, Chian Min, Hsu, Anne Ann Ling, Devanand, Anantham, Lim, Chong Hee, Koong, Heng Nung, Koh, Tina, Fong, Kam Weng, Yap, Swee Peng, Kim, Su Woon, Chowbay, Balram, Oon, Lynette, Lim, Kiat Hon, Lim, Wan Teck, Tan, Eng Huat, Tan, Daniel Shao Weng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425557/
https://ncbi.nlm.nih.gov/pubmed/25955322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123587
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