Differential effects of the complement peptides, C5a and C5a des Arg on human basophil and lung mast cell histamine release.

The ability of purified anaphylatoxins to induce human lung mast cell mediator release was investigated. In eight anti-IgE responsive (histamine release = 22 +/- 5%, mean +/- SEM) mast cell preparations of 1-96% purity, C5a and C5a des Arg (0.55 pg/ml to 55 micrograms/ml), failed to elicit or potent...

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Библиографические подробности
Главные авторы: Schulman, E S, Post, T J, Henson, P M, Giclas, P C
Формат: Artigo
Язык:Inglês
Опубликовано: 1988
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC442545/
https://ncbi.nlm.nih.gov/pubmed/2449462
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