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Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletions.

The low density lipoprotein (LDL) receptors in fibroblasts from 132 subjects with the clinical syndrome of homozygous familial hypercholesterolemia were analyzed by immunoprecipitation with an anti-LDL receptor monoclonal antibody. 16 of the 132 cell strains (12%) synthesized no immunodetectable LDL...

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Detaylı Bibliyografya
Asıl Yazarlar: Hobbs, H H, Leitersdorf, E, Goldstein, J L, Brown, M S, Russell, D W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1988
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC442544/
https://ncbi.nlm.nih.gov/pubmed/3343347
Etiketler: Etiketle
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