Thymus in myasthenia gravis. Isolation of T-lymphocyte lines specific for the nicotinic acetylcholine receptor from thymuses of myasthenic patients.

The thymus is believed to play a central role in the pathogenesis of Myasthenia gravis (MG). According to a previous hypothesis, MG is initiated within the thymus by immunogenic presentation of locally produced nicotinic acetylcholine receptor (AChR) to potentially autoimmune T cells. Data of 10 con...

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Pubblicato in:	J Clin Invest
Autori principali:	Melms, A, Schalke, B C, Kirchner, T, Müller-Hermelink, H K, Albert, E, Wekerle, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2449461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113401
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