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Molecular phenotyping of T cell-mediated rejection

A new study has reported a molecular signature of T cell-mediated rejection in human kidney transplant biopsy samples that is enriched for effector T cells, interferon-γ and macrophages. Inhibitors of T cell activation, such as CTLA4 and PDL1, were also prominent, raising the possibility that these...

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Pubblicato in:Nat Rev Nephrol
Autori principali: Chong, Anita S., Perkins, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425203/
https://ncbi.nlm.nih.gov/pubmed/25347945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2014.197
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