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Molecular phenotyping of T cell-mediated rejection
A new study has reported a molecular signature of T cell-mediated rejection in human kidney transplant biopsy samples that is enriched for effector T cells, interferon-γ and macrophages. Inhibitors of T cell activation, such as CTLA4 and PDL1, were also prominent, raising the possibility that these...
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Pubblicato in: | Nat Rev Nephrol |
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Autori principali: | , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2014
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4425203/ https://ncbi.nlm.nih.gov/pubmed/25347945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2014.197 |
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