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Amphipathic segment of the nicotinic receptor alpha subunit contains epitopes recognized by T lymphocytes in myasthenia gravis.

Autoimmune helper T lymphocytes were selected from the blood of two myasthenic patients of different HLA-DR type, using acetylcholine receptor (AChR) from Torpedo californica. These polyclonal T cell lines were tested for reactivity with three synthetic peptides corresponding to the NH2-terminal reg...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Hohlfeld, R, Toyka, K V, Miner, L L, Walgrave, S L, Conti-Tronconi, B M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2449458/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113369
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