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Expression of the Aryl Hydrocarbon Receptor in Growth Plate Cartilage and the Impact of Its Local Modulation on Longitudinal Bone Growth

Although dioxin has been reported to impair bone growth in both humans and animals, the underlying mechanisms have not been clarified. We conducted this study to rule out if dioxin may directly target the growth plate, via local modulation of the aryl hydrocarbon receptor (AhR). Initial studies in r...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cedervall, Therése, Lind, Pia Monica, Sävendahl, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425067/
https://ncbi.nlm.nih.gov/pubmed/25867478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16048059
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