Towards causally cohesive genotype–phenotype modelling for characterization of the soft-tissue mechanics of the heart in normal and pathological geometries

A scientific understanding of individual variation is key to personalized medicine, integrating genotypic and phenotypic information via computational physiology. Genetic effects are often context-dependent, differing between genetic backgrounds or physiological states such as disease. Here, we anal...

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Publicat a:J R Soc Interface
Autors principals: Nordbø, Øyvind, Gjuvsland, Arne B., Nermoen, Anders, Land, Sander, Niederer, Steven, Lamata, Pablo, Lee, Jack, Smith, Nicolas P., Omholt, Stig W., Vik, Jon Olav
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2015
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424664/
https://ncbi.nlm.nih.gov/pubmed/25833237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.1166
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