Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis.

We examined the effect of insulin and plasma amino acid concentrations on leucine kinetics in 15 healthy volunteers (age 22 +/- 2 yr) using the euglycemic insulin clamp technique and an infusion of [1-14C]leucine. Four different experimental conditions were examined: (a) study one, high insulin with...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Castellino, P, Luzi, L, Simonson, D C, Haymond, M, DeFronzo, R A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3316280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113272
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