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Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities

BACKGROUND: Cellular antiviral activities are critically controlled by transcriptional activation of interferon-inducible genes, involving interferon regulatory factors (IRFs). Previous data suggested that IRF1 is an activator and IRF2 is a repressor, which functionally antagonize each other in tran...

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Bibliographic Details
Published in:Cell Biosci
Main Authors: Ren, Gang, Cui, Kairong, Zhang, Zhiying, Zhao, Keji
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424430/
https://ncbi.nlm.nih.gov/pubmed/25960866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0007-0
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