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Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation

Delayed engraftment is a major limitation of cord blood transplantation (CBT), due in part to a defect in the cord blood (CB) cells’ ability to home to the bone marrow. Because this defect appears related to low levels of fucosylation of cell surface molecules that are responsible for binding to P-...

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Publicado en:Blood
Main Authors: Popat, Uday, Mehta, Rohtesh S., Rezvani, Katayoun, Fox, Patricia, Kondo, Kayo, Marin, David, McNiece, Ian, Oran, Betul, Hosing, Chitra, Olson, Amanda, Parmar, Simrit, Shah, Nina, Andreeff, Michael, Kebriaei, Partow, Kaur, Indreshpal, Yvon, Eric, de Lima, Marcos, Cooper, Laurence J. N., Tewari, Priti, Champlin, Richard E., Nieto, Yago, Andersson, Borje S., Alousi, Amin, Jones, Roy B., Qazilbash, Muzaffar H., Bashir, Qaiser, Ciurea, Stefan, Ahmed, Sairah, Anderlini, Paolo, Bosque, Doyle, Bollard, Catherine, Molldrem, Jeffrey J., Chen, Julianne, Rondon, Gabriela, Thomas, Michael, Miller, Leonard, Wolpe, Steve, Simmons, Paul, Robinson, Simon, Zweidler-McKay, Patrick A., Shpall, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424412/
https://ncbi.nlm.nih.gov/pubmed/25778529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-607366
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