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Redox Signal-mediated Enhancement of the Temperature Sensitivity of Transient Receptor Potential Melastatin 2 (TRPM2) Elevates Glucose-induced Insulin Secretion from Pancreatic Islets

Transient receptor potential melastatin 2 (TRPM2) is a thermosensitive Ca(2+)-permeable cation channel expressed by pancreatic β cells where channel function is constantly affected by body temperature. We focused on the physiological functions of redox signal-mediated TRPM2 activity at body temperat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kashio, Makiko, Tominaga, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424372/
https://ncbi.nlm.nih.gov/pubmed/25817999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649913
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