Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN

We previously identified Treponema pallidum repeat proteins TprC/D, TprF, and TprI as candidate outer membrane proteins (OMPs) and subsequently demonstrated that TprC is not only a rare OMP but also forms trimers and has porin activity. We also reported that TprC contains N- and C-terminal domains (...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Anand, Arvind, LeDoyt, Morgan, Karanian, Carson, Luthra, Amit, Koszelak-Rosenblum, Mary, Malkowski, Michael G., Puthenveetil, Robbins, Vinogradova, Olga, Radolf, Justin D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424362/
https://ncbi.nlm.nih.gov/pubmed/25805501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629188
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