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Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis, and Loss of Both Systems Compromises Survival of Mice under Cold Stress

The importance of brown adipose tissue as a site of nonshivering thermogenesis has been well documented. Emerging studies suggest that skeletal muscle is also an important site of thermogenesis especially when brown adipose tissue function is lacking. We recently showed that sarcolipin (SLN), an unc...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rowland, Leslie A., Bal, Naresh C., Kozak, Leslie P., Periasamy, Muthu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424359/
https://ncbi.nlm.nih.gov/pubmed/25825499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.637603
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