A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR Enzyme

The lysine methyltransferase (KMT) SETMAR is implicated in the response to and repair of DNA damage, but its molecular function is not clear. SETMAR has been associated with dimethylation of histone H3 lysine 36 (H3K36) at sites of DNA damage. However, SETMAR does not methylate H3K36 in vitro. This...

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Udgivet i:J Biol Chem
Main Authors: Carlson, Scott M., Moore, Kaitlyn E., Sankaran, Saumya M., Reynoird, Nicolas, Elias, Joshua E., Gozani, Or
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Genomics and Proteomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424340/
https://ncbi.nlm.nih.gov/pubmed/25795785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641530
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