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Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum

Phosphodiesterase 10A (PDE10A) is a dual substrate PDE that can hydrolyze both cGMP and cAMP. In brain, PDE10A is almost exclusively expressed in the striatum. In several studies, PDE10A has been implicated in regulation of striatal output using either specific inhibitors or PDE10A knock-out mice an...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Russwurm, Corina, Koesling, Doris, Russwurm, Michael
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424333/
https://ncbi.nlm.nih.gov/pubmed/25762721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595769
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