Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with the skin cancer-prone disease, xeroderma pigmentosum.

A shuttle vector plasmid, pZ189, was utilized to assess the types of mutations that cells from a patient with xeroderma pigmentosum, complementation group D, introduce into ultraviolet (UV) damaged, replicating DNA. Patients with xeroderma pigmentosum have clinical and cellular UV hypersensitivity,...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Seetharam, S, Protić-Sabljić, M, Seidman, M M, Kraemer, K H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3680516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113248
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