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Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice.

Transgenic B6C3F1 mice carrying a lacI target gene were exposed to acute and multiple doses of ethylnitrosourea (ENU), and germ cells from the seminiferous tubules were assayed for mutation 3 and 90 days after treatment. Relative to untreated controls, the mutation frequency increased 3.2- and 19.9-...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Provost, G S, Short, J M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8022821/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.14.6564
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