Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

PURPOSE: Pathological studies suggest that neuroinflammation is exacerbated by increased beta-amyloid (Aβ) levels in the brain early in Alzheimer’s disease (AD). The time course and relationships between astrocytosis and Aβ deposition were examined using multitracer in vivo positron emission tomogra...

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Udgivet i:Eur J Nucl Med Mol Imaging
Main Authors: Rodriguez-Vieitez, Elena, Ni, Ruiqing, Gulyás, Balázs, Tóth, Miklós, Häggkvist, Jenny, Halldin, Christer, Voytenko, Larysa, Marutle, Amelia, Nordberg, Agneta
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424277/
https://ncbi.nlm.nih.gov/pubmed/25893384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3047-0
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