Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

BACKGROUND: Brain metastases are common in human epidermal growth factor receptor (Her)-2-positive breast cancer. Drug access to brain metastases and normal brain is key to management of cranial disease. In this study, positron emission tomography (PET) scanning after administration of radiolabelled...

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Vydáno v:EJNMMI Res
Hlavní autoři: Saleem, Azeem, Searle, Graham E, Kenny, Laura M, Huiban, Mickael, Kozlowski, Kasia, Waldman, Adam D, Woodley, Laura, Palmieri, Carlo, Lowdell, Charles, Kaneko, Tomomi, Murphy, Philip S, Lau, Mike R, Aboagye, Eric O, Coombes, Raoul C
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424224/
https://ncbi.nlm.nih.gov/pubmed/25977884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0103-5
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