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ALTERATIONS IN THE MEDULLARY ENDOCANNABINOID SYSTEM CONTRIBUTE TO AGE-RELATED IMPAIRMENT OF BAROREFLEX SENSITIVITY

As they age, Sprague-Dawley (SD) rats develop elevated systolic blood pressure associated with impaired baroreflex sensitivity (BRS) for control of heart rate. We previously demonstrated in young hypertensive (mRen2)27 rats that impaired BRS is restored by CB(1) cannabinoid receptor blockade in the...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Schaich, Chris L., Shaltout, Hossam A., Grabenauer, Megan, Thomas, Brian F., Gallagher, Patricia E., Howlett, Allyn C., Diz, Debra I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424182/
https://ncbi.nlm.nih.gov/pubmed/25636077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000216
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