Depot Medroxyprogesterone Acetate (DMPA) Use is Associated with Elevated Innate Immune Effector Molecules in Cervicovaginal Secretions of HIV-1-uninfected Women

OBJECTIVE: The effects of sex hormones on the immune defenses of the female genital mucosa and its susceptibility to infections are poorly understood. The injectable hormonal contraceptive depot medroxyprogesterone acetate (DMPA) may increase risk of HIV-1 acquisition. We assessed the local concentr...

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Vydáno v:J Acquir Immune Defic Syndr
Hlavní autoři: Guthrie, Brandon L., Introini, Andrea, Roxby, Alison C., Choi, Robert Y., Bosire, Rose, Lohman-Payne, Barbara, Hirbod, Taha, Farquhar, Carey, Broliden, Kristina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424097/
https://ncbi.nlm.nih.gov/pubmed/25622059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000533
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