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Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.

Alpha 1-antitrypsin (alpha 1AT) deficiency resulting from homozygous inheritance of the Z-type alpha 1AT gene is associated with serum alpha 1AT levels of less than 50 mg/dl and the development of emphysema in the third to fourth decades. Despite the overwhelming evidence that the emphysema of PiZZ...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ogushi, F, Fells, G A, Hubbard, R C, Straus, S D, Crystal, R G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC442392/
https://ncbi.nlm.nih.gov/pubmed/3500183
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