A Novel Quantitative Hemolytic Assay Coupled with Restriction Fragment Length Polymorphisms Analysis Enabled Early Diagnosis of Atypical Hemolytic Uremic Syndrome and Identified Unique Predisposing Mutations in Japan

For thrombotic microangiopathies (TMAs), the diagnosis of atypical hemolytic uremic syndrome (aHUS) is made by ruling out Shiga toxin-producing Escherichia coli (STEC)-associated HUS and ADAMTS13 activity-deficient thrombotic thrombocytopenic purpura (TTP), often using the exclusion criteria for sec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yoshida, Yoko, Miyata, Toshiyuki, Matsumoto, Masanori, Shirotani-Ikejima, Hiroko, Uchida, Yumiko, Ohyama, Yoshifumi, Kokubo, Tetsuro, Fujimura, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423893/
https://ncbi.nlm.nih.gov/pubmed/25951460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124655
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