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The Role of Interleukin-10 and Hyaluronan in Murine Fetal Fibroblast Function In Vitro: Implications for Recapitulating Fetal Regenerative Wound Healing

BACKGROUND: Mid-gestation fetal cutaneous wounds heal scarlessly and this has been attributed in part to abundant hyaluronan (HA) in the extracellular matrix (ECM) and a unique fibroblast phenotype. We recently reported a novel role for interleukin 10 (IL-10) as a regulator of HA synthesis in the fe...

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Pubblicato in:PLoS One
Autori principali: Balaji, Swathi, King, Alice, Marsh, Emily, LeSaint, Maria, Bhattacharya, Sukanta S., Han, Nathaniel, Dhamija, Yashu, Ranjan, Rajeev, Le, Louis D., Bollyky, Paul L., Crombleholme, Timothy M., Keswani, Sundeep G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423847/
https://ncbi.nlm.nih.gov/pubmed/25951109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124302
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