Heterozygous genome assembly via binary classification of homologous sequence

BACKGROUND: Genome assemblers to date have predominantly targeted haploid reference reconstruction from homozygous data. When applied to diploid genome assembly, these assemblers perform poorly, owing to the violation of assumptions during both the contigging and scaffolding phases. Effective tools...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Autores principales: Bodily, Paul M, Fujimoto, M Stanley, Ortega, Cameron, Okuda, Nozomu, Price, Jared C, Clement, Mark J, Snell, Quinn
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423727/
https://ncbi.nlm.nih.gov/pubmed/25952609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S7-S5
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