Heterozygous genome assembly via binary classification of homologous sequence

BACKGROUND: Genome assemblers to date have predominantly targeted haploid reference reconstruction from homozygous data. When applied to diploid genome assembly, these assemblers perform poorly, owing to the violation of assumptions during both the contigging and scaffolding phases. Effective tools...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Bodily, Paul M, Fujimoto, M Stanley, Ortega, Cameron, Okuda, Nozomu, Price, Jared C, Clement, Mark J, Snell, Quinn
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423727/
https://ncbi.nlm.nih.gov/pubmed/25952609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S7-S5
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