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Experimental Colitis Is Associated with Transcriptional Inhibition of Na(+)/Ca(2+) Exchanger Isoform 1 (NCX1) Expression by Interferon γ in the Renal Distal Convoluted Tubules

NCX1 is a Na(+)/Ca(2+) exchanger, which is believed to provide a key route for basolateral Ca(2+) efflux in the renal epithelia, thus contributing to renal Ca(2+) reabsorption. Altered mineral homeostasis, including intestinal and renal Ca(2+) transport may represent a significant component of the p...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Radhakrishnan, Vijayababu M., Kojs, Pawel, Ramalingam, Rajalakshmy, Midura-Kiela, Monica T., Angeli, Peter, Kiela, Pawel R., Ghishan, Fayez K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423686/
https://ncbi.nlm.nih.gov/pubmed/25648899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.616516
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