Unique ATPase Site Architecture Triggers cis-Mediated Synchronized ATP Binding in Heptameric AAA(+)-ATPase Domain of Flagellar Regulatory Protein FlrC

Bacterial enhancer-binding proteins (bEBPs) oligomerize through AAA(+) domains and use ATP hydrolysis-driven energy to isomerize the RNA polymerase-σ(54) complex during transcriptional initiation. Here, we describe the first structure of the central AAA(+) domain of the flagellar regulatory protein...

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Vydáno v:J Biol Chem
Hlavní autoři: Dey, Sanjay, Biswas, Maitree, Sen, Udayaditya, Dasgupta, Jhimli
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423664/
https://ncbi.nlm.nih.gov/pubmed/25688103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611434
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