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Unique ATPase Site Architecture Triggers cis-Mediated Synchronized ATP Binding in Heptameric AAA(+)-ATPase Domain of Flagellar Regulatory Protein FlrC
Bacterial enhancer-binding proteins (bEBPs) oligomerize through AAA(+) domains and use ATP hydrolysis-driven energy to isomerize the RNA polymerase-σ(54) complex during transcriptional initiation. Here, we describe the first structure of the central AAA(+) domain of the flagellar regulatory protein...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423664/ https://ncbi.nlm.nih.gov/pubmed/25688103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611434 |
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