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Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes.

Myocardial hypertrophy in vivo is associated with reexpression of contractile protein isogenes characteristic of fetal and neonatal development. The molecular signals for hypertrophy and isogene switching are unknown. We studied alpha (sarcomeric)-actin messenger RNA (mRNA) expression in cultured ca...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Bishopric, N H, Simpson, P C, Ordahl, C P
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1987
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2821075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113179
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