Furaldehyde substrate specificity and kinetics of Saccharomyces cerevisiae alcohol dehydrogenase 1 variants

BACKGROUND: A previously discovered mutant of Saccharomyces cerevisiae alcohol dehydrogenase 1 (Adh1p) was shown to enable a unique NADH-dependent reduction of 5-hydroxymethylfurfural (HMF), a well-known inhibitor of yeast fermentation. In the present study, site-directed mutagenesis of both native...

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Détails bibliographiques
Publié dans:Microb Cell Fact
Auteurs principaux: Laadan, Boaz, Wallace-Salinas, Valeria, Carlsson, Åsa Janfalk, Almeida, João RM, Rådström, Peter, Gorwa-Grauslund, Marie F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423641/
https://ncbi.nlm.nih.gov/pubmed/25287956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0112-5
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