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Effects of Brain-Derived IL-2 Deficiency and the Development of Autoimmunity on Spatial Learning and Fear Conditioning

Interleukin-2 (IL-2) has been implicated in neurological disorders including multiple sclerosis and Alzheimer’s disease. Peripheral IL-2 deficiency in gene-deleted mice results in T cell mediated autoimmunity that begins to develop slowly after weaning and progressively increases through adulthood....

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Detalles Bibliográficos
Publicado en:J Neurol Disord
Main Authors: Petitto, John M., Cushman, Jesse D., Huang, Zhi
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423554/
https://ncbi.nlm.nih.gov/pubmed/25961067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-6895.1000196
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