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Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats.

Among characterized forms of liver microsomal cytochromes P-450 in rats are four related isozymes (P-450f-i) notable for their lack of inducibility. Immunoblot analyses demonstrated that human livers microsomes contained several proteins related to these rat P-450s. A human liver P-450, termed HLx,...

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Publicat a:J Clin Invest
Autors principals: Wrighton, S A, Thomas, P E, Willis, P, Maines, S L, Watkins, P B, Levin, W, Guzelian, P S
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3654967/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113154
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