Chelation of dietary iron prevents iron accumulation and macrophage infiltration in the type I diabetic kidney

We previously reported that the functional deletion of p21, a cyclin-dependent kinase inhibitor, in mice attenuated renal cell senescence in streptozotocin (STZ)-induced type 1 diabetic mice. In the present study, we investigated the effect of iron chelation on renal cell senescence and inflammation...

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Bibliografske podrobnosti
izdano v:Eur J Pharmacol
Main Authors: Morita, Tatsuyori, Nakano, Daisuke, Kitada, Kento, Morimoto, Satoshi, Ichihara, Atsuhiro, Hitomi, Hirofumi, Kobori, Hiroyuki, Shiojima, Ichiro, Nishiyama, Akira
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423393/
https://ncbi.nlm.nih.gov/pubmed/25820160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2015.03.053
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