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Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation

Guidepost cells present at and surrounding the midline provide guidance cues that orient the growing axons through commissures. Here we show that the transcription factor Nkx2.1 known to control the specification of GABAergic interneurons also regulates the differentiation of astroglia and polydendr...

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Publicat a:Nat Commun
Autors principals: Minocha, Shilpi, Valloton, Delphine, Ypsilanti, Athena R., Fiumelli, Hubert, Allen, Elizabeth A., Yanagawa, Yuchio, Marin, Oscar, Chédotal, Alain, Hornung, Jean-Pierre, Lebrand, Cécile
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423212/
https://ncbi.nlm.nih.gov/pubmed/25904499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7887
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