Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by rat hepatic 3 alpha-hydroxysteroid dehydrogenase. I. Studies with the purified enzyme, isolated rat hepatocytes, and inhibition by indomethacin.

We recently identified that the Y' bile acid binders are 3 alpha-hydroxysteroid dehydrogenases (3 alpha-HSD). In the present studies, purified 3 alpha-HSD catalyzed rapid 3H loss from [3 beta-3H, C24-14C]lithocholic and chenodeoxycholic acids without net conversion to 3-oxo bile acids under physiolo...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Takikawa, H, Stolz, A, Kaplowitz, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3476498/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113143
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!